This research seeks to determine the relationship between the United States and Russia about five major events: the war in Afghanistan, the competition for energy resources in the Caspian Sea, the war in Iraq, the expansion of the North Atlantic Treaty Organization (NATO), and the Russian invasion of Ukraine. Smart PLS 3.0 is used to acquire and analyze the data for this study, which is based on 78 respondents. Five major events, including the war in Afghanistan, the competition for energy resources in the Caspian Sea, the war in Iraq, the expansion of the North Atlantic Treaty Organization (NATO), and the Russian invasion of Ukraine, have significantly disrupted the relationship between the United States and Russia, according to this research. This research is founded on primary data collected to determine its findings. As a result of the research findings, this study significantly contributes to the existing body of knowledge. This research has important theoretical implications that must be considered for this study. In addition, the research has some practical implications that should be considered when attempting to improve relations between the United States and Russia. To contribute to the body of knowledge, prospective researchers must consider certain future directions of this research.