As the trade dynamics shifted, it became vital to strengthen international contacts. In addition, developing technology has enabled firms to conduct business beyond international borders. Therefore, this study aims to investigate the impact of information and communication technologies on international relations. In addition, the role of international innovation and entrepreneurial promotion as mediators between the relationship of information and communication technology and international relations was investigated. PLS-SEM was utilized to analyze data gathered from 300 employees of Iraqi international organizations. According to the study's findings, organizations' information and communication technologies support the development of worldwide innovation and the promotion of entrepreneurship. In addition, the results demonstrated that international innovation, entrepreneurial encouragement, and international trade sequentially moderate the interaction between information and communication technologies and international relations.